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TCP (Tenocyclidine)  known more formally as N-[1-(2-thienyl)cyclohexyl] piperidine, is an
analog of phencyclidine (PCP) in which the phenyl substituent is replaced with a thiophene
group. Tenocyclidine (TCP, thienyl cyclohexylpiperidine) is a dissociative anesthetic drug with
stimulant and hallucinogenic effects. It is similar in effects to phencyclidine but is considerably
more potent.

Pharmacodynamics
TCP has slightly different binding properties to PCP, with more affinity for the NMDA
receptors, but less affinity for the sigma receptors. however its increased psychostimulant
effects compared to PCP suggests it also has relatively greater activity as a dopamine
reuptake inhibitor (DRI)

Type
Small Molecule
Purity
=98%
Molecular Formula
C15H23NS HCl

SHIPPING & STORAGE
Storage
-20C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
= 2 years
Tenocyclidine (TCP, thienylcyclohexylpiperidine, C15H23NS) is an analog of phencyclidine
(PCP)
TCP in combination with atropine was observed to protect acetylcholinesterase in
organophosphate and carbamate poisoning

Tenocyclidine hydrochloride
Properties
form  solid
drug control  USDEA Schedule I; regulated under CDSA - not available from Sigma-
Aldrich Canada
color  white
solubility  H2O: soluble
methanol: soluble
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